Sound-induced artifact in cochlear blood flow measurements using the laser Doppler flowmeter.
نویسندگان
چکیده
The laser Doppler flowmeter has been shown to give a response from the cochlea during high intensity acoustic stimulation which is not related to blood flow through the cochlea. The magnitude of this response depends upon the intensity and frequency of stimulation and the location of the probe on the cochlea. Evidence is presented that the response is derived from the vibration of cochlear tissue and/or the bony cochlear shell during acoustic stimulation.
منابع مشابه
Laser Doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig.
This investigation examined the effects of loud sound of different frequencies and intensities on cochlear blood flow as measured by the laser Doppler flowmeter. Cochlear blood flow was measured in anesthetized guinea pigs during a 1 h exposure to either a 2, 4, or 12 kHz pure tone or high-pass noise (10-40 kHz) at 90, 103, or 110 dB SPL. Cochlear function was assessed using the compound action...
متن کاملCochlear blood flow increases after systemic hemodilution: comparison of simultaneous laser Doppler flowmetry and radioactive microsphere measurements.
Guinea pig cochlear blood flow was measured before and after systemic normovolemic hemodilution with high molecular weight dextran. Absolute determinations of blood flow (in the cochlea, brain, kidney and lung) were accomplished by use of radioactive-labeled (85Sr or 141Ce) microspheres. Relative measurements of the cochlear blood flow changes were made simultaneously by the use of a laser Dopp...
متن کاملMECHANISMS OF BLOOD FLOW INCREASE INDUCED BY ELECTRICAL STIMULATION
Previous studies have shown that electrical stimulation (ES) increases blood flow, but the exact mechanisms are not clear. The present study was designed to clarify some of the underlying mechanisms involved in this phenomenon. White adult rabbits Lt.-6 months old were used. Animals were anesthetized by sodium pentobarbital (40 mg/kg, IV) and skin blood flow in the thoracic back was recorde...
متن کاملDetection of Site-Specific Blood Flow Variation in Humans during Running by a Wearable Laser Doppler Flowmeter
Wearable wireless physiological sensors are helpful for monitoring and maintaining human health. Blood flow contains abundant physiological information but it is hard to measure blood flow during exercise using conventional blood flowmeters because of their size, weight, and use of optic fibers. To resolve these disadvantages, we previously developed a micro integrated laser Doppler blood flowm...
متن کاملTissue blood flow measurement by laser Doppler technique
Measurement of blood flow and the effects of different factors on tissue blood flow are important fields of research in physiology and pharmacology. So far, different methods have been innovated, using laser light is the Last one. In this article history, principles and specifications of laser technique along with its advantages and disadvantages ( in comparison with other methods) are revie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Hearing research
دوره 31 3 شماره
صفحات -
تاریخ انتشار 1987